50 citations,
March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
50 citations,
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46 citations,
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42 citations,
May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
35 citations,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
33 citations,
October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
33 citations,
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31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
29 citations,
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29 citations,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
24 citations,
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24 citations,
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21 citations,
January 1991 in “Dermatology” Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.
21 citations,
May 1989 in “Advanced Drug Delivery Reviews” Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
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19 citations,
July 2006 in “Physiology & Behavior” Finasteride slows down motherly behavior in first-time pregnant rats.
17 citations,
April 2007 in “Kidney international” Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
16 citations,
March 2000 in “Clinical Biochemistry” Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
15 citations,
June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
13 citations,
January 2022 in “Advances in Dermatology and Allergology” Alopecia areata may be linked to imbalanced gut bacteria.
12 citations,
January 2011 in “Dermatologic Surgery” Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.
11 citations,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
11 citations,
January 2018 in “Asian Journal of Andrology” Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
11 citations,
March 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
10 citations,
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March 2020 in “Metabolites” Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
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October 2018 in “Dermatologic Therapy” About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
7 citations,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.