July 1996 in “Annals of Internal Medicine” Long-term high-dose fluconazole can cause reversible hair loss.
180 citations,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
4 citations,
August 2022 in “The Scientific World Journal” Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
April 2023 in “International Journal of Women's Dermatology” Spironolactone is safe for breast cancer survivors with alopecia and does not increase cancer risk.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
30 citations,
August 2021 in “Journal of Ethnopharmacology” Akebia quinata and Akebia trifoliata have many health benefits and potential medical uses.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” TLR2, a component in hair follicle stem cells, is crucial for healthy hair growth and regeneration, and its decrease can lead to hair loss.
January 2023 in “Brazilian Journal of Pharmaceutical Sciences” A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.
33 citations,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.
31 citations,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
26 citations,
May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
20 citations,
February 2017 in “European journal of pharmaceutical sciences” The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.
16 citations,
October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Dutasteride may protect the brain in early Parkinson's disease.
14 citations,
May 2020 in “Biomolecules & Therapeutics” Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
12 citations,
March 2017 in “Arteriosclerosis, thrombosis, and vascular biology” Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
4 citations,
October 2022 in “American journal of physiology. Heart and circulatory physiology” Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
4 citations,
February 2022 in “Experimental Dermatology” Hair loss in men might be linked to changes in cell energy factories.
3 citations,
April 2022 in “Neuroscience Letters” Finasteride may help treat autism by reducing inflammation and oxidative stress.
1 citations,
March 2024 in “Science” Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
September 2023 in “JEADV Clinical Practice” People with common hair loss conditions may have a higher risk of heart disease and related health issues.
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
37 citations,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
9 citations,
May 2021 in “Frontiers in aging neuroscience” Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
8 citations,
February 2022 in “Scientific Reports” Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.
7 citations,
December 2019 in “Pharmaceutics” Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
6 citations,
October 2014 in “Experimental Dermatology” Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
4 citations,
December 2023 in “Advanced science” New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.
1 citations,
January 2022 in “Faculty reviews” The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.