research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
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research C19 and C21 5β/5α Metabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Association Between Male Pattern Baldness and Testicular Germ Cell Tumor: A Meta-Analysis
Baldness may lower the risk of testicular cancer.
research What Should the Hair Clinician Know About Hair Transplants?
Hair transplants are effective for male and female pattern baldness, have evolved in technique, and require careful planning for natural results and managing complications.
research Anticancer Drugs in Surface Waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Promotion of Homology-Directed DNA Repair by Polyamines
Polyamines help fix DNA damage accurately in cells.
research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
research Teriflunomide (Aubagio) for the Treatment of Multiple Sclerosis
Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.
research Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research 5α-Reductase Activity in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
research The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model
Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
research Medical Treatment of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia
Treatment for benign prostatic hyperplasia involves drugs that either quickly relieve symptoms or reduce prostate size, with a combination offering more benefits but more side effects.
research Structural Characterization of Cyclosporin A, C, and Microbial Bio-Transformed Cyclosporin A Analog AM6 Using HPLC–ESI–Ion Trap-Mass Spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Deoxycorticosterone’s Anticonvulsant Effects in Infant Rats Are Blocked by Finasteride, but Not by Indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Brain Allopregnanolone Induces Marked Scratching Behavior in Diet-Induced Atopic Dermatitis Mouse Model
A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
research Prolonged Hypotension Induced by Ingesting a Topical Minoxidil Solution: Analysis of Minoxidil and Its Metabolites
Swallowing a lot of minoxidil, a hair growth liquid, can cause severe and long-lasting low blood pressure.
research Hot Stuff: Thermal Imaging Aids in Cellulitis Diagnosis
The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
research Microbial Oxidation of Finasteride with Macrophomina Phaseolina (KUCC 730)
research The Association of Male Pattern Baldness and Risk of Cancer and High-Grade Disease Among Men Presenting for Prostate Biopsy
Men with more advanced male pattern baldness have a higher risk of prostate cancer and more severe disease.
research Early Postnatal Neuroactive Steroid Manipulation Differentially Affects Recognition Memory and Passive Avoidance Performance in Male Rats
Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.
research Age, What Age, How Old? A Study on Androgenetic Alopecia Progression in Men Over 5 Years with Placebo Treatment
Untreated androgenetic alopecia leads to progressive hair loss in men.
research A Case-Control Study of Physical Activity, Obesity, and Energy Intake and the Risk of Kidney Cancer
Being obese and eating too many calories may increase the risk of kidney cancer, but physical activity doesn't seem to affect this risk.
research Prostate Specific Antigen Levels in Diabetic and Non-Diabetic Men from the 2001–2002 National Health and Nutrition Examination Survey
Long-term diabetes is linked to lower prostate cancer risk.
research Body Mass Index Is Associated With Increased Risk Of Aggressive And Decreased Risk Of Non-Aggressive Prostate Cancer
Higher BMI is linked to a lower risk of non-aggressive prostate cancer and a higher risk of aggressive prostate cancer.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome
Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.