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LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.

Proper mineral supplementation in cow-calf operations prevents health issues and economic losses.

Exosomes are important for skin health and could help diagnose and treat skin diseases.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Finasteride affects young male rats' brain function and behavior negatively.

Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

Future work on macrolide antibiotic analysis will aim to enhance selectivity, sensitivity, and efficiency using advanced chromatographic methods.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.