7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
5 citations,
November 2022 in “Journal of Ginseng Research/Journal of ginseng research” Ginsenoside Re from Panax ginseng may prevent hair loss by maintaining autophagy and Wnt signaling in hair cells.
4 citations,
August 2023 in “Biomedicine & Pharmacotherapy” The study demonstrates that ivacaftor, a CFTR potentiator, protects against noise-induced hair cell loss and hearing loss by increasing Nrf2 expression and reducing oxidative stress. Using in-vivo FVB/NJ mice and in-vitro HEI-OC1 cell models, ivacaftor was shown to significantly reduce oxidative stress markers and preserve hair cell function. The protective effects of ivacaftor were found to be Nrf2-dependent, suggesting its potential as a therapeutic agent for noise-induced hearing loss. The research was supported by grants from the National Natural Science Foundation of China and the National Institutes of Health, USA.
2 citations,
February 2023 in “International journal of molecular sciences” Tetrathiomolybdate reduces hair growth marker in skin cells by boosting harmful oxygen molecules, but effects can be reversed.
2 citations,
January 2023 in “Scientific Reports” HIF-1α is important for hair growth and could be a treatment target for hair loss.
1 citations,
January 2024 in “International journal of molecular sciences” MicroRNAs could be key biomarkers and therapeutic targets for PCOS.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
1 citations,
April 2023 in “Frontiers in Immunology” New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
1 citations,
February 2023 in “ACS Biomaterials Science & Engineering” The new microwell device helps grow more hair stem cells that can regenerate hair.
1 citations,
May 2022 in “Frontiers in Psychiatry” Hair loss was the first sign of a brain-related complication in a woman with lupus, and early treatment helped her hair grow back.
1 citations,
February 2022 in “Clinical, Cosmetic and Investigational Dermatology” TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
May 2024 in “Archives of dermatological research” Enz_MoriL from mulberry leaves helps hair growth by affecting specific cell pathways.
May 2024 in “Indian Journal of Dermatology” Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.
September 2023 in “International journal of molecular sciences” Targeting lipid metabolism can help treat advanced, resistant cancers.
August 2023 in “IntechOpen eBooks” Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.
355 citations,
January 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
277 citations,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
153 citations,
June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
146 citations,
September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
142 citations,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
137 citations,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
136 citations,
October 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
107 citations,
April 2014 in “The Plant cell” The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.
84 citations,
March 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
75 citations,
September 2009 in “Dermato-endocrinology” The skin produces and processes hormones, affecting both local and overall body functions.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
42 citations,
September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
36 citations,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
28 citations,
June 2015 in “Journal of circadian rhythms” An individual's morning or evening preference can predict changes in their body clock gene expression.