research iNOS Inhibits Hair Regeneration in Obese Diabetic (ob/ob) Mice
iNOS contributes to hair loss in obese diabetic mice and blocking it may encourage hair growth.
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research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Recognizing Polycystic Ovary Syndrome in the Primary Care Setting
Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.
research Polycystic Ovary Syndrome: Pathophysiology, Diagnosis, and Treatment
PCOS is a common hormonal disorder in women that can lead to serious health problems.
research Assessment of Chemokines MIP-1α and MIP-1β in Iraqi Women with Polycystic Ovarian Syndrome
PCOS is linked to low-grade chronic inflammation.
research Hidradenitis Suppurativa, Acne Inversa, Dissecting Terminal Hair Folliculitis
Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
research Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss
People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
research Protective Effects of BCC Against Oxidative Stress in Cardiomyocyte Cells
BCC can protect heart cells from damage caused by oxidative stress.
research The Role of ADAM17 in PCOS Pathogenesis: A Review Paper
ADAM17 could be a potential target for treating PCOS.
research Type A Insulin Resistance Syndrome Due to a Novel Heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR Gene Mutation in an Adolescent Girl and Her Mother
A new gene mutation causes insulin resistance in a girl and her mother.
research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Cancer Risk in Polycystic Ovary Syndrome Patients: Common Treatments and Future Perspectives
PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
research Telogen Effluvium, Diagnosis and Management: A Narrative Review
Hair loss from Telogen Effluvium can be managed by treating the underlying cause and may improve with treatments like minoxidil.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
research Pattern of Cutaneous Manifestations of Diabetes Mellitus
Over half of the diabetes patients had skin issues, with fungal infections being most common.
research Dysfunction of Hair Follicle Mesenchymal Progenitors Is Associated with Age-Related Hair Loss
Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Integration of Magnetic Tweezers and Traction Force Microscopy for Exploring the Mechanobiology of Keratinocyte Cell-Cell and Cell-Matrix Anchoring Junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
research Elevated Expression of Osteopontin Splice Variants in Nonmelanoma Skin Cancer Compared to Normal Skin and Adult Keratinocytes
Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
research RPGRIP1L Facilitates Desmosomal Adhesion Through Suppressing PKCβII-Mediated Desmoglein Endocytosis: Implication in Pemphigus
RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.
research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells
Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research S2 PSA: Reliable or Not Reliable?
PSA testing is a reliable method for detecting prostate cancer, and opioids may lower PSA levels, but triglycerides don't affect prostate cancer risk.
research Urethral PSA Levels After Radical Prostatectomy
Higher urethral PSA levels after prostate removal surgery may be linked to more hair loss and higher PSA levels post-surgery.
research S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research Is Radical Prostatectomy the Best Choice for Patients with Locally Advanced Prostate Cancer?
The document does not confirm if radical prostatectomy is the best treatment for locally advanced prostate cancer.
research Serum Triglyceride Concentration and Risk of Prostate Cancer: A Prospective Multicenter Study
Serum triglyceride levels are not linked to prostate cancer risk.