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Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.

Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.

Keratins are crucial for cell structure, growth, and disease risk.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.