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Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.

People with alopecia areata have higher insulin resistance.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Non-immune factors play a significant role in alopecia areata.

Autoimmune and metabolic issues are linked, and treating one may worsen another.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Model improves accuracy in predicting hair loss effects.

Metformin is less effective in men with early-onset hair loss.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.