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Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Improving skin barrier and using antifungal treatments can help manage dandruff.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

To manage diffuse hair loss, identify the cause, improve nutrition, remove triggers, and use specific treatments like minoxidil or finasteride.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Mannosylerythritol lipids are good for skin and hair care products.

Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

New treatments for male hypogonadism are effective and should be personalized.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.