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Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Larger ovarian size is linked to higher insulin resistance in women with PCOS.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Skin fat helps with body temperature control and has other active roles in health.

Lower SHBG levels may increase the risk of PCOS.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Excess androgens may cause PCOS, not just be a symptom.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

A male with aromatase deficiency improved bone health with estradiol treatment.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.