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Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

The study identified key genes and pathways linked to hair disorders, aiding precision medicine.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.

Patients with central centrifugal cicatricial alopecia often have higher rates of metabolic, autoimmune, and atopic conditions, as well as anxiety and depression.

Child abuse is linked to higher BMI, but not because of hair cortisol or cortisone levels.

Non-immune factors play a significant role in alopecia areata.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Women with PCOS have different levels of certain metabolites in their blood, which could help diagnose and predict the condition.

Adipokines affect skin health and could be targeted for treating skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

New cytokine-targeted therapies show promise for treating alopecia areata.

Skin and nail problems like hair loss, dry skin, and fungal infections are common in people with long-term Type 2 Diabetes and can be prevented with good blood sugar control and foot care.

The document explains the genetic causes and characteristics of inherited hair disorders.

Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.

Male-pattern baldness has a weak link to heart disease and some related health conditions.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Manipulating cell cleanup processes could help treat hair loss.

Ferulic acid may help control menstrual cycle-related epilepsy by affecting female hormones.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.

Effective PCOS treatments require targeting specific signaling pathways.

The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Female hair loss linked to metabolic syndrome, not in males.