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Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Metformin improves early signs of heart disease in women with PCOS and raises apelin levels, but doesn't significantly change artery thickness.

Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.

Dsg1 is essential for maintaining a healthy skin barrier in mice.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Fat cells are important for tissue repair and stem cell support in various body parts.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.

IMA and IMA/albumin levels don't predict alopecia areata severity.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Pantethine may boost the immune system's ability to fight sarcoma.