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Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

Pregnancy can cause skin changes and may affect pre-existing skin conditions, with some treatments not safe for use during pregnancy.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Hair loss linked to higher heart disease risk in both men and women.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Non-immune factors play a significant role in alopecia areata.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

Women with epilepsy on certain medications might gain weight and have higher thyroid-stimulating hormone levels, but not more polycystic ovarian syndrome.

Hair loss in women linked to higher sexual dysfunction risk.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.