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Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Nutritional supplements may help improve hair growth in female pattern hair loss.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

People with vitiligo may have a lower risk of heart disease.

Combination therapy helped patient with advanced Hidradenitis Suppurativa achieve remission.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Finasteride overdose can cause acute pancreatitis.