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Hyperandrogenism is a common hormonal disorder in women, often linked to PCOS.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Spironolactone most effective for hirsutism, but has side effects.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Finasteride reduces hair growth and is safe for women with excessive hair.

Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Thyroid receptor agonists may treat male pattern baldness without harmful side effects.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Men with male pattern baldness have a higher chance of heart disease, especially if they're younger or have severe baldness; no link was found with another type of baldness called alopecia areata.

Pranlukast and mirabegron may work as new diabetes drugs.

Metformin improves early signs of heart disease in women with PCOS and raises apelin levels, but doesn't significantly change artery thickness.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Acne in reproductive-age women may be linked to conditions like PCOS and lifestyle factors, so doctors should check for these when treating acne.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The rapid corticotropin test is a quick and simple way to diagnose adrenal insufficiency.