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Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Aging can lead to poorer scalp and hair health, including less hair and more scalp diseases, which should be managed to help older people feel better.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Hair loss linked to higher heart disease risk in both men and women.

Skin fat helps with body temperature control and has other active roles in health.

Lower SHBG levels may increase the risk of PCOS.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.