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Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Probiotic bacteria improved skin and hair health in aged mice.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Spermidine helps protect against aging by preserving telomere length.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Finasteride helps treat hair loss by blocking enzyme activity.

Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Finasteride's potential harms are hard to accurately measure.

Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.

Low-glycemic index diets are beneficial for weight loss and satiety, but more research is needed on long-term effects and individualized approaches are recommended.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.