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This study found that young men with early-onset androgenetic alopecia have a worse glycolipid profile and hormone pattern similar to women's PCOS, suggesting a possible male PCOS-equivalent syndrome.

This review examines various methods for purifying extracellular vesicles loaded with drugs, highlighting their principles, benefits, and drawbacks, and stresses the importance of standardized guidelines to enhance the reproducibility of EV-based drug delivery research.

This systematic review identified robust biomarkers associated with hidradenitis suppurativa and confirmed potential drugs for repurposing, highlighting key pathogenetic pathways and their links to comorbid disorders.

This article is a letter to the editor about high-dose pulsed corticosteroid therapy combined with methotrexate for severe childhood alopecia areata and provides no new clinical results.

This meta-analysis found that patients with androgenetic alopecia have significantly abnormal lipid profiles, which could contribute to the link between this condition and cardiovascular diseases.

This study found no significant association between androgenetic alopecia and metabolic syndrome, though systolic blood pressure was higher in the alopecia group compared to controls.

This report advances the hypothesis that finasteride and dutasteride inhibit 5α-reductase activities, potentially altering steroid metabolism and increasing the risk of insulin resistance, diabetes, and vascular disease.

This study found that the MTHFR gene C677T mutation appears to be a susceptibility factor for alopecia areata in the Turkish population.

This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.

This study found that girls with polycystic ovary syndrome and longer SHBG and AR gene repeats experienced greater improvements in lipid and androgen levels after one year of metformin treatment.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

This study found that methotrexate treatment for 15 days suppressed tuberculin hypersensitivity in Strain 2 guinea pigs without causing lymphopenic or anti-inflammatory effects.

This article reviews the role of sulfhydryl compounds, particularly cystine, in sulfur metabolism and the physiology of skin in both normal and pathological conditions, reporting no new findings.

This study found that older age and obesity are predictors of metabolic syndrome and insulin resistance syndrome among infertile Vietnamese women with PCOS.

In this study, vitamin D supplementation showed no significant effect on androgen levels or clinical hyperandrogenism in PCOS women, but when combined with metformin, it improved testosterone levels.

This study found that increasing the follicle number criteria for diagnosing PCOS to 25 per ovary excluded some women who continue to show evidence of metabolic risk.

This research discusses the potential antitumor effects of metformin, a common diabetes medication, noting its controversial influence on different malignant tumors and its uncertain mechanisms. Understanding these effects on tumors may aid in the development of new cancer treatments.

This study reports that hair analysis could potentially monitor metformin use in diabetic patients, suggesting a possible correlation between daily dose and concentration in dark hair but not in light hair.

This study highlights that lower testosterone in men and higher testosterone in women are linked to increased risks of metabolic syndrome and type 2 diabetes, with associated skin diseases indicating potential cardiovascular complications.

This study found that glycolysis in Paneth cells provides lactate to support mitochondrial oxidative phosphorylation in intestinal stem cells, aiding their function and differentiation.

In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.

This study found that methylprednisolone pulse therapy may be an effective treatment option for patients with severe multifocal alopecia areata, particularly those experiencing their first episode.

This study found that irregular menstrual cycles in Brazilian adolescents were significantly associated with a higher occurrence of metabolic syndrome and polycystic ovary syndrome indicators.

This study found that the modified wash test was generally more effective than TrichoScan® for diagnosing hair loss, particularly telogen effluvium, though both methods showed only fair concordance with clinical diagnosis.

This study found that AHCC significantly reduced alopecia caused by Ara-C in neonatal rats and improved liver function affected by 6-MP and MTX in mice.

This study reports that in women with non-tumor hyperandrogenism, a decrease in serum testosterone from insulin-sensitizing therapy like metformin may indicate a low likelihood of having an androgen-secreting tumor.

This case study describes a 15-year-old girl with pulmonary Crohn's disease diagnosed via endoscopy, highlighting the potential for endobronchial changes in children with this condition.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.

This study found that early-onset androgenetic alopecia, especially with a vertex pattern, may be an independent risk factor for cardiovascular disease and metabolic syndrome in men.