March 2026 in “Preprints.org” This study found that the MIRA technique, which customizes needle length and injection angle guided by ultrasound, improved structural and esthetic outcomes for cellulite treatment compared to standard methods.
13 citations
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February 2020 in “Journal of the American Academy of Dermatology” This study found that both oral tranexamic acid and microneedling improve melasma treatment outcomes when added to standard therapy, with microneedling showing a more sustained remission.
April 2026 in “Journal of Aesthetic Medicine” This study found that the MIRA technique, using ultrasound-guided needle adjustments, improved cellulite treatment outcomes compared to standard methods in women with stage 3 cellulite, evidenced by greater reductions in adipose thickness and other skin irregularities, along with higher patient satisfaction.
5 citations
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January 2023 in “Journal of Cosmetic Dermatology” This study found that microbotox, especially when injected intradermally, effectively reduces enlarged facial pores with higher patient satisfaction and longer-lasting results compared to its topical application after microneedling.
1 citations
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January 2000 in “Journal of pharmacopuncture” This study confirmed that microneedle therapy systems (MTS) significantly improve hair growth and skin conditions, including acne and acne scars, without serious side effects.
9 citations
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August 2006 in “American Journal of Psychiatry” This case report suggests that lamotrigine treatment may be associated with hair loss as a rare side effect, based on the observation of hair regrowth after discontinuation of the drug in a single patient.
1 citations
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January 2018 in “Pediatric Dermatology” No results are reported in this piece; it is a correspondence comment on treating hidradenitis suppurativa in children with finasteride.
June 2017 in “Poster presentations” In this study, the safety profiles of four treatments for early rheumatoid arthritis were assessed over one year, and the most serious side effects necessitating treatment discontinuation were noted in the leflunomide group, whereas no such withdrawals occurred in the methotrexate plus prednisolone group.
This study found that scalp care using micro-needle therapy was effective in improving hair density and thickness in middle-aged women with menopausal symptoms compared to a control group.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
November 2025 in “Dermatology Reports” This review found that microinfusion of medications using tattoo devices (MMP®) shows potential as a minimally invasive method for treating ailments like alopecia and basal cell carcinoma, offering notable improvements with minimal side effects due to localized drug delivery.
39 citations
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March 2009 in “Clinics in plastic surgery” This review discusses the evolution and studies of injection lipolysis for fat reduction, highlighting the need for more research to ensure patient safety and treatment efficacy; it reports no new clinical results.
29 citations
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September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the efficacy and safety of 5-alpha reductase inhibitors for treating androgenetic alopecia, noting concerns about sexual side effects, which are typically uncommon and often resolve over time.
7 citations
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October 2024 in “AAPS PharmSciTech” This study developed a caffeine-loaded solid lipid nanoparticle gel, observing significant reduction in subcutaneous fat tissue thickness in histological tests compared to an untreated group, suggesting it could effectively treat cellulite as a promising nanocosmeceutical gel.
5 citations
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January 2020 in “Skin appendage disorders” This study found that oral dutasteride increased hair count more than intralesional administration in androgenetic alopecia, but more research is needed for a reliable comparison.
November 2024 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” In this study, researchers investigated the use of the Pulse Booster Drug Delivery Mesojectgun technology for non-invasive treatment of scalp conditions, finding improvements in hair volume, thickness, and reduction of hair loss in four participants with alopecia after applying specific active ingredients.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.
49 citations
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August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
January 2023 in “Skin appendage disorders” This review discusses the scalp microinfusion MMP® technique for hair loss treatment and reports no new results; it emphasizes the need for more standardized studies.
March 2023 in “Clinical Cosmetic and Investigational Dermatology” This commentary reviews methods for delivering adipose-derived mesenchymal stem cell secretome for facial skin rejuvenation and does not report new clinical results; the authors discuss addressing concerns about administration methods and product characterization.
75 citations
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November 2009 in “Gynecological Endocrinology” This study found that both myo-inositol and metformin helped restore normal menstrual cycles in patients with PCOS, but myo-inositol appeared to be more effective in inducing pregnancy.
52 citations
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May 2019 in “Journal of The American Academy of Dermatology” This study evaluated the effectiveness and safety of low-dose oral minoxidil (2.5-5 mg daily) in men with male androgenetic alopecia, aiming to contribute data to an area with limited previous reports. Results are not provided in the abstract.
36 citations
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September 2018 in “American Journal of Clinical Dermatology” This study found that a topical combination of 0.25% finasteride and 3% minoxidil may increase hair diameter more effectively than 3% minoxidil alone in postmenopausal women with female pattern hair loss.
27 citations
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November 2013 in “Dermatologic Therapy” This study suggests that a hair follicle enzyme assay may predict response to minoxidil treatment for androgenetic alopecia with high sensitivity and specificity in a preliminary analysis.
20 citations
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April 2014 in “Dermatologic Therapy” This study reported that sulfotransferase activity in plucked hair follicles can predict treatment response to 5% topical minoxidil in women with androgenetic alopecia with high sensitivity and specificity.
15 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the potential use of platelet-rich plasma for treating alopecia areata but reports no new experimental findings, noting the need for standardized protocols and larger studies to evaluate its efficacy.
8 citations
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April 2006 in “Acta dermato-venereologica” Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
7 citations
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March 2005 in “British Journal of Dermatology” This study discusses patterns of androgenetic alopecia in Indian men but reports no new clinical findings.
3 citations
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April 2003 in “BJUI” Doxazosin alone or combined with finasteride improves prostate symptoms better than finasteride alone, without extra benefits.
2 citations
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January 2022 in “Journal of Cutaneous and Aesthetic Surgery” This study suggests the mechanical effect of injecting a solution is more important than the solution's nature in treating atrophic acne scars, with UBM sonography proposed for objective assessment.