15 citations,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
27 citations,
March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
47 citations,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
2 citations,
November 2018 in “Cell Stem Cell” The research found a new way to heal chronic skin ulcers by turning certain cells into skin tissue using specific factors.
66 citations,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
3 citations,
January 2020 in “Indian Journal of Dermatology” Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.
5 citations,
January 2020 in “The mental health clinician” Vitamin D supplements may reduce hair-pulling in people with Trichotillomania.
35 citations,
January 2014 in “BioMed Research International” Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
32 citations,
December 2017 in “International Journal of Molecular Sciences” Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
31 citations,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
218 citations,
September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
7 citations,
February 2018 in “InTech eBooks” Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
December 2024 in “Medical Review” Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
May 2023 in “Experimental Dermatology” Male pattern hair loss may be linked to the developmental origins of hair follicles.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
5 citations,
January 2017 in “Dermatologic Surgery” Storing hair follicle micrografts for longer times can cause them to enter a state similar to the natural hair shedding phase, which might impact hair transplant results.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.
139 citations,
February 2014 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
8 citations,
January 2014 in “PubMed” Researchers made stem cells from human hair follicle cells with better efficiency than from skin cells.
1 citations,
June 2023 in “Journal of Cellular and Molecular Medicine” The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.
7 citations,
November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
June 2023 in “Livestock studies” The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.
26 citations,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.