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The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

Cell aging can be both good and bad for tissue repair.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Ionizing radiation damages human hair follicles by stopping cell growth, causing cell death, disrupting color, and increasing stress and damage markers.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

Dermal macrophages might help regrow hair.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

TGF-β2 plays a key role in human hair growth and development.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.