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    Did you mean Mesenchymal Stem Cell-Conditioned Medium?
    Glossary Mesenchymal Stem Cell-Conditioned Medium

    solution containing bioactive molecules secreted by mesenchymal stem cells

    Mesenchymal Stem Cell-Conditioned Medium (MSC-CM) is a solution that contains bioactive molecules secreted by mesenchymal stem cells during their growth in culture. This medium is used in regenerative medicine and research because it can promote tissue repair, reduce inflammation, and support cell growth, making it valuable for treating conditions like alopecia and other hair-related disorders.

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    1. Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review Frontiers in Cell and Developmental Biology · 2021 · 26 citations
    2. Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro Human Cell · 2026
    3. Therapeutic Approach for Hair Growth and Regeneration Using Bioactive Formulation Containing Mesenchymal Stromal Cell-Derived Conditioned Medium Journal of Cosmetics, Dermatological Sciences and Applications · 2023
    4. Conditioned Medium from Human Mesenchymal Stromal Cells: Towards the Clinical Translation International Journal of Molecular Sciences · 2019 · 166 citations
    5. In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing Cytotherapy · 2015 · 52 citations
    6. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells · 2020 · 19 citations
    7. In vitro and clinical evaluation of umbilical cord‐derived mesenchymal stromal cell‐conditioned media for hair regeneration Journal of Cosmetic Dermatology · 2021 · 2 citations
    8. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017 · 773 citations
    9. Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-II 2024
    10. The potential of Spirulina maxima extract-treated conditioned medium from adipose-derived mesenchymal stem cells for hair growth promoting effect on human dermal papilla cells Regenerative Therapy · 2025
    11. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction Biomaterials · 2017 · 182 citations
    12. Promotion of Hair Growth by Conditioned Medium from Extracellular Matrix/Stromal Vascular Fraction Gel in C57BL/6 Mice Stem Cells International · 2020 · 13 citations
    13. Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis Frontiers in Cell and Developmental Biology · 2025 · 3 citations
    14. Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome Stem Cell Research & Therapy · 2025 · 1 citations
    15. TMT-Based Quantitative Proteomic Analysis Reveals the Effect of Bone Marrow Derived Mesenchymal Stem Cell on Hair Follicle Regeneration Frontiers in Pharmacology · 2021 · 4 citations
    16. The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization Experimental Dermatology · 2009 · 131 citations
    17. Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning Frontiers in Immunology · 2018 · 320 citations
    18. Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis Stem Cell Research & Therapy · 2025 · 3 citations
    19. Emerging pharmacotherapies and regenerative solutions for promoting hair growth for androgenetic alopecia Frontiers in Pharmacology · 2026
    20. Stem Cell-Based Therapies for Hair Loss: What is the Evidence from a Clinical Perspective? Stem cell biology and regenerative medicine · 2022
    21. Extracellular vesicles released by hair follicle and adipose mesenchymal stromal cells induce comparable neuroprotective and anti-inflammatory effects in primary neuronal and microglial cultures Cytotherapy · 2023
    22. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    23. Stem Cell-Enriched Treatments in Aesthetic Medicine: A Comprehensive Scientific Literature Review of Current Applications, Mechanisms, Outcomes, and Future Perspectives 2025
    24. Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing Stem cell research & therapy · 2022 · 22 citations
    25. Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine Frontiers in Cellular Neuroscience · 2022 · 9 citations
    26. Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases Stem Cell Research & Therapy · 2025
    27. Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease Stem Cell Research & Therapy · 2020 · 118 citations
    28. Promotion of hair growth by a conditioned medium from human umbilical cord mesenchymal stem cells cultivated in a 3D scaffold of gelatin sponge European journal of medical research · 2024 · 2 citations
    29. Clinical and preclinical approach in AGA treatment: a review of current and new therapies in the regenerative field Stem Cell Research & Therapy · 2024
    30. Exploring the dermatological applications of human mesenchymal stem cell secretome: a comprehensive review Stem Cell Research & Therapy · 2025 · 9 citations