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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

New effective scar treatments are urgently needed due to the current options' limited success.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Stem cell niches support, regulate, and coordinate stem cell functions.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Minoxidil helps hair growth by activating the β-catenin pathway.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The circadian clock influences the behavior and regeneration of stem cells in the body.