314 citations,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
9 citations,
March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
3 citations,
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Curcumin applied to the skin can start hair growth in mice.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
835 citations,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
162 citations,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
155 citations,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
105 citations,
May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating TRPV3 stops human hair growth.
97 citations,
September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
56 citations,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
48 citations,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
45 citations,
May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
42 citations,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
28 citations,
September 2013 in “Journal of Investigative Dermatology” The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
26 citations,
March 2013 in “Journal of Biomedical Materials Research Part A” Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
25 citations,
November 2012 in “Phytotherapy Research” Crataegus pinnatifida extract may help increase hair growth and thickness in mice.
23 citations,
December 2004 in “Differentiation” Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
22 citations,
February 2017 in “Clinical and Experimental Dermatology” Icariin helps mouse hair grow by boosting a growth factor in skin cells.
21 citations,
March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
6 citations,
January 2016 in “Annals of Dermatology” Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.
5 citations,
October 2020 in “Journal of radiation research” Vesicles from irradiated mouse cheek skin help cells survive radiation.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
2 citations,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.