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Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.

Untreated androgenetic alopecia leads to progressive hair loss in men.

The document updates on EU legal changes, including pharmaceutical patents, class actions in Italy, and various drug-related rulings.

The UK Intellectual Property Office allows granting of supplementary protection certificates with negative terms.

The UK Court of Appeal ruled that new dosing regimens for drugs can be patented, aligning with the European Patent Office's approach.

MK-386 reduces sebum DHT levels.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.

Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Finasteride discontinuation increases sperm count in men.

UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.

Finasteride works for male hair loss only.

The author had undisclosed conflicts of interest related to the original article on post-finasteride syndrome.

Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.

Dosage regime inventions can be patentable in China, but legal uncertainty exists.

The article concludes that recent legal rulings have strengthened the protection of pharmaceutical patents against generic competition.

Europe strengthened medicine regulations, increased protection against counterfeit drugs, and made it tougher to challenge comparative advertising, while also focusing on patent law enforcement and updating plant protection rules.

The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.

A new protein linked to Alzheimer's was discovered, and a hair loss treatment showed effectiveness but had some sexual side effects.

Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.

Dermatologists are more comfortable and proactive in treating male pattern hair loss than primary care physicians.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Some psychiatric medications can cause hair loss, but stopping or reducing the dose usually reverses it.

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

Minoxidil ingestion can cause severe heart issues and requires careful medical monitoring.

A woman lost all her hair after overdosing on divalproex, but it grew back while still on the medication.