April 2026 in “Biomedicines” This perspective outlines the current understanding and knowledge gaps in the cellular and molecular mechanisms of wound healing, highlighting their implications for pathological conditions like keloids and chronic wounds, and reviews potential novel therapies for these issues.
February 2026 in “NeuroSci” This systematic review synthesizes evidence on the distribution of 5a-reductase isozymes and their implications for mental health, finding that inhibition of neurosteroidogenesis may contribute to anxiety, depression, and suicidality, with some patients experiencing persistent psychiatric effects from finasteride or dutasteride.
October 2025 in “Current Pharmaceutical Research” This study evaluated a new herbal shampoo made from traditional plants and found it to have effective cleansing properties, moderate foam stability, and environmental safety, suggesting it as a favorable natural alternative to synthetic shampoos.
January 2025 in “African Journal of Biomedical Research” This abstract discusses the holistic approach of homeopathy to treating alopecia, emphasizing individualized care by considering a person's unique physical, emotional, and mental characteristics, but does not report specific study results.
September 1961 in “Archives of Dermatology” This correspondence questions the assertion in a 1961 article that lichen sclerosus et atrophicus does not lead to carcinoma, citing a case contrary to the author's claim.
9 citations
,
December 2024 in “Clinical and Experimental Obstetrics & Gynecology” This review examines the impact of polycystic ovary syndrome on reproductive health, its pathophysiology, clinical manifestations, and emerging therapies, and reports no new findings; the authors emphasize the need for individualized treatment strategies.
5 citations
,
November 2020 in “EBioMedicine” This study reports a novel diagnostic method for latent circadian rhythm sleep-wake disorder using circadian gene oscillations from hair follicle cells to improve sleep disorder differentiation and potential therapeutic intervention.
1514 citations
,
December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
556 citations
,
September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
363 citations
,
May 2006 in “Current Opinion in Psychiatry” This review highlights that medical complications, notably in anorexia nervosa, are common and often serious in patients with eating disorders, affecting multiple organ systems.
139 citations
,
December 2021 in “Journal of Clinical Medicine” This systematic review reports that fatigue was the most common symptom in both phases of long COVID, with lung function issues more frequent in the ongoing symptomatic phase and psychological burdens like anxiety and depression more prevalent in the post-COVID syndrome phase.
114 citations
,
December 1951 in “Archives of Dermatology” This article reviews the effectiveness of adrenal cortex compounds E and F in treating various connective tissue disorders and reports no new clinical findings.
95 citations
,
July 2010 in “Genes & development” In this study, the researchers reported that Notch/CSL signaling is crucial for hair follicle differentiation, with Wnt5a signaling and FoxN1 acting as mediators in mice.
68 citations
,
January 2008 in “Seminars in reproductive medicine” This narrative review discusses the impact of polycystic ovary syndrome on women's psychological and sexual well-being, highlighting the potential benefits of interdisciplinary treatments and new interventions to improve life satisfaction and coping, but reports no new results.
65 citations
,
April 2021 in “Natural Products and Bioprospecting” This review discusses the traditional uses and pharmacologically active compounds of 22 Dendrobium species for dermatological disorders but reports no new results, highlighting the need for further research.
55 citations
,
August 2008 in “Reviews in endocrine and metabolic disorders” This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.
55 citations
,
January 2007 in “Climacteric” This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.
55 citations
,
December 2006 in “Journal of The American Academy of Dermatology” This review discusses the potential for SSRIs to cause serious skin reactions and suggests considering alternative antidepressants if such reactions occur.
54 citations
,
May 2018 in “International journal of risk & safety in medicine” This study observed enduring sexual dysfunction reported in 300 cases globally following the use of SSRIs, finasteride, and isotretinoin, with common symptoms like genital anaesthesia and loss of libido.
48 citations
,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” This article reviews gender differences in skin disorders, highlighting variations in disease prevalence and type between sexes, but reports no new findings, emphasizing potential implications for prevention and treatment strategies.
48 citations
,
September 2009 in “Dermato-endocrinology” This article reviews skin signs in patients with anorexia nervosa and their potential role in early diagnosis but reports no clinical results; it emphasizes the importance of dermatologists in recognizing these signs.
46 citations
,
May 2020 in “Cureus” This review analyzes the molecular and genetic roles of zinc, its connection to diarrheal disease, dietary recommendations, and the impacts of zinc deficiency on health, but reports no new data.
42 citations
,
January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
41 citations
,
March 2010 in “Psychology Research and Behavior Management” This review discusses the complex interplay between the nervous system and skin conditions, highlighting various treatment strategies, but reports no new research findings.
37 citations
,
January 1997 in “Clinics in Dermatology” This study found that women with androgenetic alopecia and alopecia areata had significantly lower serum ferritin levels compared to women without hair loss.
33 citations
,
April 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses the skin conditions linked to eating disorders and emphasizes that treating the underlying disorder often improves these dermatological symptoms.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.
31 citations
,
November 2000 in “Journal of the European Academy of Dermatology and Venereology” This article discusses the diverse dermatological symptoms associated with sexual abuse, highlighting the challenges in establishing causal links and the potential long-term psychosomatic manifestations, without reporting new research results.
29 citations
,
September 1989 in “Journal of The American Academy of Dermatology” This article describes cases of unusual scalp whorl patterns, including triple parietal and right temporal whorls, that were associated with normal development, and discusses theories of hair whorl development.
28 citations
,
October 2018 in “Clinical Obstetrics and Gynecology” This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.