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The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Dianabol boosts muscle growth but has serious health risks and legal issues.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Excessive blue light harms eye cells and disrupts sleep patterns.

Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.

COVID-19 has widely affected health, various industries, and the economy, but also led to more remote work and less pollution.

Finasteride users have a very low risk of mental health issues, but those with hair loss may have slightly higher anxiety and depression.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

PFS might be a delusional disorder with potential to become mass psychogenic illness.

A woman's health issues were caused by arsenic poisoning from kelp supplements.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Long COVID patients have more health issues than non-infected people.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Women with PCOS have more emotional and body image issues than healthy women.

Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).

Shift work disrupts the body's natural clock, leading to health problems.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Low ferritin and Vitamin D levels may cause hair loss after COVID-19.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

People with certain skin disorders are more likely to have alcohol problems, especially if they also have mental health issues like depression and anxiety.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.