February 2026 in “Editora Pasteur eBooks” An integrative approach combining medical, nutritional, and lifestyle changes effectively manages female pattern hair loss.
January 2026 in “Forum Dermatologicum” This review analyzed scientific literature and found that dermatological symptoms, such as hirsutism and acne, frequently appear as early indicators of PCOS, reflecting hormonal imbalances and aiding diagnosis of the disorder.
November 2025 in “International Journal of Clinical Obstetrics and Gynaecology” This study found evidence for a genetic basis of polycystic ovary syndrome, indicating an autosomal dominant pattern of inheritance among first-degree relatives.
January 2025 in “International Journal of Unani and Integrative Medicine” This review explores hirsutism in women with PCOS, analyzing its pathophysiology and management through both modern medicine and Unani perspectives, and suggests combining these approaches for more holistic care, while calling for future research to enhance treatment efficacy and safety.
March 2024 in “Journal of Rawalpindi Medical College/Journal Rawalpindi Medical College” This study observed that skin conditions like hirsutism, acne, and androgenic alopecia were common in PCOS patients and may aid in its diagnosis.
January 2024 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that combining minoxidil 0.1% and dutasteride 0.01% applied topically after microneedling was significantly more effective than using dutasteride alone with microneedling in improving female pattern hair loss in 40 female patients.
November 2023 in “Curēus” This study, conducted in Jeddah, Saudi Arabia, found that women with PCOS who consumed diets high in carbohydrates, fats, and refined sugars had a significant prevalence of obesity and struggled with weight loss, with fast food consumption notably associated with facial acne.
July 2023 in “Dermatology practical & conceptual” This study found that women with Female Pattern Hair Loss had lower serum BDNF levels, which correlated with higher stress and depression, suggesting BDNF as a potential marker for psychological impacts in these patients.
July 2023 in “Endocrinology, diabetes & metabolism case reports” This case report involved a premenopausal woman with rapidly progressing virilizing symptoms caused by a rare sertoliform endometrioid carcinoma of the ovary. Following surgical intervention, her symptoms improved, highlighting the importance of recognizing virilizing symptoms as potential indicators of low-grade ovarian malignancies in similar cases.
December 2015 in “Kosin Medical Journal” This review discusses the diagnosis, symptoms, metabolic complications, and treatment options for polycystic ovary syndrome but reports no new findings.
January 2014 in “European Geriatric Medicine” A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Iron deficiency is not more common in women with hair loss, and neurogenic rosacea may need different treatment.
June 1995 in “International Journal of Gynecology & Obstetrics” This article provides citations without reporting new findings on androgen conjugate levels in alopecia.
January 2023 in “Indian Dermatology Online Journal” This study found that female pattern hair loss in Western India is often associated with metabolic syndrome, which correlates with earlier onset and increased severity.
January 2020 in “International Journal of Trichology” This case study reported two instances of female androgenetic alopecia with male pattern reversed after surgical removal of an ovarian tumor.
4025 citations
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December 2003 in “Human Reproduction” This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.
1514 citations
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December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
212 citations
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May 2010 in “American Journal of Obstetrics and Gynecology” This article suggests using only firm criteria to diagnose polycystic ovary syndrome in adolescents, due to the evolving nature of its features during this period.
120 citations
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June 2008 in “American Journal of Epidemiology” This study reported a 6.3% prevalence of PCOS among women in a Sri Lankan community, with most cases presenting as oligo/amenorrhea and polycystic ovaries.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” This review outlines the challenges in diagnosing hyperandrogenism in women, focusing on its manifestations like hirsutism, acne, and virilization, but provides no new results.
71 citations
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July 2015 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS have elevated serum androgen levels throughout adulthood, with these levels decreasing and variations increasing as they approach menopause.
56 citations
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July 2008 in “European journal of endocrinology” This study found that a 6-month treatment with either metformin or rosiglitazone significantly improved endothelial function in young women with PCOS without any one drug being superior.
39 citations
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September 2000 in “Obstetrics and Gynecology Clinics of North America” This article reviews evidence on hyperinsulinemia and insulin resistance in women with polycystic ovary syndrome and evaluates therapeutic responses to insulin-lowering agents, reporting no new clinical findings.
34 citations
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June 2010 in “Archives of Disease in Childhood” This review discusses normal menstrual variations and common menstrual disorders in adolescent girls, focusing on symptoms, evaluation, and management, but does not present new clinical results.
14 citations
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September 2017 in “Clinics in Dermatology” This study highlights that lower testosterone in men and higher testosterone in women are linked to increased risks of metabolic syndrome and type 2 diabetes, with associated skin diseases indicating potential cardiovascular complications.
6 citations
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September 2025 in “Scientific Reports” This study found that using XGBoost with clinical and ultrasound features may provide a highly accurate, non-invasive method for diagnosing polycystic ovary syndrome, although further validation is needed to ensure robustness.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
2 citations
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June 2024 in “Anti-Aging Eastern Europe” This review discusses the varied clinical presentations and management challenges of Polycystic Ovary Syndrome across different life stages, reporting no new clinical findings.
1 citations
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November 2020 in “Cureus” This study found that severity of female pattern hair loss in premenopausal women was related to other clinical signs of hyperandrogenism like hirsutism and acne, but not to biochemical measures of hyperandrogenism.
In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.