December 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that in South Asian women with PCOS, the severity of non-alcoholic fatty liver disease is strongly linked to early renal dysfunction, as indicated by increased serum creatinine and urinary albumin levels, and reduced eGFR.
This review discusses polycystic ovary syndrome, focusing on its primary features of ovulatory dysfunction and hyperandrogenism, and reports no new findings.
18 citations
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March 2015 in “Journal of Endocrinological Investigation” This study found that ZP4 expression was highest among PCOS patients with regular menstrual cycles, which may be linked to mature follicle presence, but no correlation with clinical indices was observed.
January 2023 in “International journal of medical science and health research” This study found that anovulatory PCOS patients were younger, had longer menstrual cycles, and higher systolic blood pressures compared to ovulatory patients.
This study found that resveratrol improved ovarian function, menstrual irregularities, hair loss, and sex hormone levels in patients with polycystic ovary syndrome compared to placebo.
6 citations
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April 2019 in “Journal of Pediatric Endocrinology and Metabolism” In this study, metformin improved BMI, menstrual regularity, and symptoms of hyperandrogenism in adolescents with type 1 diabetes, but did not enhance glycemic control.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
8 citations
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February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
1 citations
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January 2025 in “ARC Journal of Nursing and Healthcare” This study focused on overweight and obese women with polycystic ovary syndrome who underwent lifestyle modification interventions and found notable improvements in BMI, menstrual cycle regularities, hyper-androgenic symptoms, and fertility outcomes, including a 36.2% pregnancy rate post-intervention.
January 2026 in “AYUSHDHARA” This case study highlights that an Ayurvedic treatment approach involving Basti Chikitsa and Tilmooladi Churna over 3 months may improve menstrual regularity and hormonal profiles in a woman with polycystic ovary syndrome.
July 2025 in “International Journal of Ayurvedic Medicine” In this pilot study, Kantavallabha rasa, an Ayurvedic medicine, showed significant improvements in PCOS symptoms such as menstrual irregularities, pain, unwanted hair growth, skin issues, and ovarian conditions among 10 women with PCOS.
July 2025 in “International Journal of Homoeopathic Sciences” This case study observed that individualized homoeopathic treatment with Calcarea carbonica led to improvements in psychological stability, general well-being, and various symptoms of hypothyroidism, including menstrual regularity and hair fall reduction, in a 27-year-old female patient over six months.
48 citations
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February 2014 in “Fertility and Sterility” This study found that androgenic alopecia is present in 22% of women with polycystic ovary syndrome and is associated with acne and hirsutism, but not with increased biochemical hyperandrogenemia or metabolic dysfunction beyond PCOS.
40 citations
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April 2008 in “European journal of endocrinology” In this study, treatment with insulin sensitizers significantly increased adipose tissue GLUT4 mRNA expression and improved insulin resistance, menstrual patterns, and androgen profiles in PCOS patients, with rosiglitazone being more effective than metformin.
June 2026 in “International Journal of Drug Delivery Technology” This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.
60 citations
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February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
46 citations
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December 2007 in “International Journal of Cardiology” This study found that patients with polycystic ovary syndrome have reduced heart rate recovery, an exaggerated systolic blood pressure response to exercise, and decreased heart rate variability, implying possible autonomic dysfunction.
7 citations
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August 2019 in “Journal of Ovarian Research” This study reported that both phlebotomy and oral contraceptive pills with cyproterone acetate effectively improved insulin resistance and androgenic profiles in women with PCOS, but OCs had more impact on regularizing menstrual cycles.
1 citations
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December 2024 in “Bulletin of Osh State University” This review highlights the significant risks posed by mercury to the endocrine system, including disruptions in hormone synthesis and regulation, stress response, and potential reproductive dysfunction, while noting the need for further research on dose-response relationships and long-term impacts.
January 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this case study, a 20-year-old female with hypothyroidism experienced marked symptom improvement, including weight reduction and menstrual regularization, after Ayurvedic management involving herbal remedies and lifestyle changes, suggesting Ayurveda could complement conventional therapies and indicating the need for larger-scale validation.
July 2025 in “JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES” This study describes a case in which a 24-year-old woman with PCOS symptoms, including irregular menstruation and excessive hair growth, showed significant improvement in androgen levels, menstrual regularity, and hair reduction after undergoing a nine-month Ayurvedic treatment plan with dietary and lifestyle modifications.
August 2024 in “Journal of Contemporary Medical Practice” In this analysis, Professor Ma Shuanquan attributes androgenetic alopecia to liver, spleen, and kidney dysfunctions and describes a treatment approach using Chinese medicines focused on these organs, suggesting individualization and noting significant therapeutic effects.
April 2024 in “Canadian Women s Health Today” This review suggests that "polycystic ovarian syndrome" is a misleading name, as the disorder involves complex metabolic and reproductive issues beyond ovarian dysfunction and may stem from factors affecting the fetus in utero.
March 2024 in “International journal of life-sciences scientific research/SSR Institute of International Journal of Life Sciences” This systematic review reported that PCOS is marked by increased androgens, hirsutism, and an elevated LH/FSH ratio, with metformin showing a therapeutic effect on menstrual cycles, emphasizing the need for individualized treatment strategies.
August 2023 in “International Journal For Multidisciplinary Research” This case study reported that using the ayurvedic treatment protocol of Nitya Virechana, Kulatthadi Kashaya, and Shatapushpa Churna was associated with improved menstrual regularity, reduced obesity, and decreased symptoms of hirsutism and acne in a 19-year-old woman with PCOD.
July 2022 in “International journal of medical science and clinical invention” In this case report, a 17-year-old girl with secondary amenorrhea was evaluated for PCOS, highlighting the importance of assessing abnormal menstrual patterns for underlying conditions, and suggesting that hormonal birth control and lifestyle changes can help manage symptoms.
January 2022 in “Acta Scientific Women's Health” This autobiographical case study describes a 25-year-old woman with PCOS who successfully managed her symptoms using hormonal therapy, including oral contraceptives and Myo-Inositol, leading to normalized menstrual cycles and the resolution of most symptoms.
3 citations
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June 2004 in “Reviews in gynaecological practice” This review reports that treating polycystic ovary syndrome in adolescents with anti-androgens and weight loss is beneficial, and suggests that metformin may be useful for symptom management and prevention.
September 2025 in “Obstetrics and gynecology.” This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.
This review discusses the diagnosis, symptoms, and treatment options for polycystic ovary syndrome but reports no new research findings; the authors emphasize the importance of early diagnosis and treatment to reduce complications.