23 citations
,
November 2018 in “Development, Growth & Differentiation” This review discusses the role of stem cell heterogeneity and compartmentalization within the epidermis and highlights their significance as niches for neighboring cells, without reporting new experimental results.
23 citations
,
February 2015 in “International Journal of Molecular Sciences” This study found that colchicine treatment significantly reduced hair fiber elongation in cultured hair follicles and altered protein expression and activity in dermal papilla cells, suggesting a role for the ubiquitin-proteasome system in its effects.
23 citations
,
November 2007 in “Journal of cosmetic dermatology” This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.
20 citations
,
January 2014 in “International Journal of Trichology” This study found that early onset androgenetic alopecia in young Asian Indian Gujarati men is independently associated with an increased risk of coronary artery disease.
19 citations
,
August 2018 in “International Journal of Dermatology” In this study, lupus panniculitis of the scalp was associated with a high incidence of recurrence and progression to systemic lupus erythematosus, despite various treatments showing complete response within weeks.
19 citations
,
March 2012 in “Clinical Endocrinology” This study established a normative free androgen index range of 0.7-6.4 and identified a cut-off value of 6.1 for reproductive-age women in southern China, highlighting hyperandrogenic women's increased metabolic disorder risks.
18 citations
,
May 2017 in “Head & Neck” This study reported that free tissue transfer for postcranioplasty implant exposure led to a 100% free flap survival rate and salvaged 91% of the implants without removal, suggesting it is a highly effective reconstructive option even for chronic cases.
17 citations
,
June 2002 in “Dermatologic Surgery” This study found that, compared to Caucasian individuals, bald Chinese patients have a lower follicular unit density, and implanting an average of 30 FUs/cm² can effectively reconstruct a natural frontal hairline.
17 citations
,
April 1997 in “Archives of dermatology” This case report describes the treatment of hirsutism in a 15-year-old obese Mexican girl with flutamide, aiming to improve her social function.
16 citations
,
April 2016 in “PLoS ONE” In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.
16 citations
,
December 2010 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study determined that the upper normal cut-off levels for free testosterone, dehydroepiandrosterone sulfate, and total testosterone among reproductive-age women in China are 26 pmol/L, 4.92 μmol/L, and 2.39 nmol/L, respectively.
13 citations
,
September 2019 in “EBioMedicine” This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.
13 citations
,
April 2015 in “Journal of Dermatology” In this study, long-term finasteride treatment improved androgenetic alopecia in Japanese men, with younger age and less advanced disease at treatment start predicting better efficacy.
13 citations
,
March 2012 in “The Journal of Dermatology” This study reports that transplanted mouse hair follicles restored piloerection ability and connected properly with host tissues, suggesting potential for advanced hair restoration therapies.
12 citations
,
March 2019 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy increased the expression of proteins in dermal papilla tissues, suggesting it promotes hair growth in male androgenetic alopecia patients.
11 citations
,
July 2016 in “Endocrinology” This study found that higher Lnk expression in PCOS patients may contribute to insulin resistance by inhibiting insulin signaling pathways.
10 citations
,
November 2010 in “Journal of Dermatology” In this study, the researchers reported that finasteride's efficacy in treating female pattern hair loss in Japanese patients was not predictable based on CAG repeat numbers in the androgen receptor gene.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
10 citations
,
January 2007 in “Dermatology” This study reported higher levels of certain proteins, such as DAX-1, SRY, and WT-1, in the bald scalp of patients with androgenetic alopecia.
9 citations
,
November 2017 in “International Journal of Nanomedicine” This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.
9 citations
,
September 2012 in “Clinical Endocrinology” This study found that over half of the patients experienced varying degrees of hair loss after acromegaly surgery, with female patients and those with severe postoperative growth hormone deficiency more commonly affected.
8 citations
,
May 2022 in “International journal of nanomedicine” This study developed a fully natural resveratrol nanoparticle system using lecithin, showing potent anti-cancer activity in vitro and increased tumoral uptake in vivo on breast cancer models.
5 citations
,
October 2018 in “Journal of Clinical Laboratory Analysis” This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.
5 citations
,
February 2015 in “Dermatologica Sinica” In this study, a computer-aided imaging system accurately measured the width of balding areas in female pattern hair loss, correlating strongly with clinical staging severity.
5 citations
,
December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
4 citations
,
March 2022 in “Cureus” This study found that applying minced residual skin grafts to donor sites significantly reduced healing time and improved scar quality compared to untreated sites.
3 citations
,
January 2018 in “İstanbul Kuzey Klinikleri” This study found that 37.4% of high-school students in rural Eskisehir had alopecia, with affected students experiencing poorer health-related quality of life, particularly in general health perception, vitality, and mental health.
3 citations
,
July 2015 in “Dermatologica Sinica” This study found that dermoscopy is increasingly accepted among Taiwanese dermatologists, with its use more common among women, younger practitioners, and those with dermoscopy training.
2 citations
,
November 2020 in “International Journal of Otorhinolaryngology and Head and Neck Surgery” The researchers reported that nasolabial flaps were effective for reconstructing small to intermediate oral cavity defects in early oral cancer patients, with overall good cosmetic and functional outcomes despite some complications.
2 citations
,
March 2015 in “Dermatologic Therapy” Using too much minoxidil foam can cause a rare movement disorder with facial twitching, but symptoms go away when the correct dose is used.