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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The Rotterdam Study aims to understand various diseases in older adults.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Tempol is safe and may prevent hair loss from brain radiotherapy.

Fat cells in the skin help start healing and form important repair cells after injury.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.

New treatments for male hypogonadism are effective and should be personalized.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.

New alopecia treatments aim for better results and fewer side effects.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.