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PDRN helps repair tissue and improve wound healing with a high safety profile.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Skin problems are very common in people with end-stage kidney disease.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Vitiligo causes white skin patches and is linked to autoimmune issues.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Improving the environment and cell interactions is key for creating human hair in the lab.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.