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Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Estrogen therapy can reduce skin aging but has cancer risks.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Nerves and chemicals in the body can affect hair growth and loss.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Prolactin affects hair growth cycles and can cause early hair follicle regression.