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The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Fullerenes show potential in skin care but need more safety research.

Nerves and chemicals in the body can affect hair growth and loss.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.