research Recently Identified Forms of Epidermolysis Bullosa
Three new types of a skin blistering disease were found, caused by specific gene mutations.
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research Dermatologic Manifestations of Thyroid Disease: A Literature Review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research Reactive Oxygen Species: Beneficial Companions of Plant Developmental Processes
Reactive oxygen species (ROS) help control plant growth and development.
research Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes
Cysteine helps maintain keratin production in skin cells even when iron is low.
research Cisd2 Deficiency Impairs Neutrophil Function by Regulating Calcium Homeostasis via Calnexin and SERCA
Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
research Liposomes in Dermatology Today
Liposomes improve drug delivery and reduce skin irritation in dermatology.
research Melanocytes: The New Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Expression of the SCUBE3 Epidermal Growth Factor-Related Gene During Early Embryonic Development in the Mouse
Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.
research Bead-Jet Printing Enabled Sparse Mesenchymal Stem Cell Patterning Augments Skeletal Muscle and Hair Follicle Regeneration
Bead-jet printing of stem cells improves muscle and hair regeneration.
research Melatonin Modulates Tomato Root Morphology by Regulating Key Genes and Endogenous Hormones
Melatonin improves tomato root growth and plant health at certain levels by affecting genes and hormones but can damage roots at high levels.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Application of Acyzol in the Context of Zinc Deficiency and Perspectives
Acyzol could help treat conditions caused by zinc deficiency.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Association of Insulin Resistance with Hyperandrogenism in Women
Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Non-Invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases: A Focus on Psoriasis and Lupus Erythematosus
Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
research Melatonin Promotes Hair Regeneration by Modulating the Wnt/β-Catenin Signaling Pathway
Melatonin helps hair grow by activating a specific signaling pathway.
research Keratin Film Made of Human Hair as a Nail Plate Model for Studying Drug Permeation
Keratin films from human hair can potentially replace human nail plates for drug testing.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Melatonin Induces a Stimulatory Action on the Scrotal Skin Components of Soay Ram in the Non-Breeding Season
Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Special Collection on Inward Rectifying Potassium Channels
Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Functional Characterization of Soybean Strigolactone Biosynthesis and Signaling Genes in Arabidopsis MAX Mutants and GmMAX3 in Soybean Nodulation
GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.
research Epithelial Loss of Mitochondrial Oxidative Phosphorylation Leads to Disturbed Enamel and Impaired Dentin Matrix Formation in Postnatal Developed Mouse Incisor
Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.