research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
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research Going Beyond Hair: Seven Simple Actions to Help Prevent Major Illness in Hair Transplant Patients
Hair transplant surgeons should also focus on their patients' overall health, including regular check-ups and screening for common health issues.
research Silk-Inspired In Situ Hydrogel with Enhanced Anti-Tumor Immunity for Photodynamic Therapy in Melanoma and Infected Wound Healing
The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type Over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair Are Risk Factors
Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
research Association Between Nodular Melanoma Depth and Area-Based Socioeconomic Status, Healthcare Access, and Preventive Services Use in the United States
Melanoma thickness at diagnosis is linked to access to dermatologists and preventive services, not to socioeconomic status.
research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade
Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.
research Melanotic Pigmentation in Excisional Scar of Melanoma Patient Who Received BRAF and MEK Inhibitors
Patients with melanoma who saw dermatologists and were from higher-income areas were more likely to have follow-up visits, which was linked to lower mortality.
research Reply to Finasteride and Dutasteride May Reduce Melanoma Risk
Finasteride and dutasteride may lower melanoma risk, with teenage acne possibly indicating higher risk.
research Melanocyte Pigmentation – Friend or Foe on the Route to Melanoma
Darker skin provides more protection against UV damage and cancer.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Automated Skin Surface Phenotype for Melanoma Risk Assessment
An automated method accurately assesses melanoma risk using 3D body images to analyze skin traits.
research Deep Learning Model to Predict Sentinel Lymph Node Status in Melanoma Patients
The AI model somewhat predicts lymph node status in melanoma patients using skin sample images.
research Hair Repigmentation as a Melanoma Warning Sign
Hair turning darker can be a sign of skin cancer.
research Melanoma Follow-Up and Mortality: A Large-Scale Study of Medicare Patients
Regular follow-up visits, especially with dermatologists, can lower death rates for melanoma patients, with socioeconomic factors also affecting outcomes.
research Melanoma Prognosis in the United States: A State-Based Analysis of Associated Factors
Melanoma survival rates vary by state and are better where incomes are higher, more people have health insurance and education, and there are more dermatologists.
research Role of Observation for Excisionally Biopsied Moderately Dysplastic Nevi with Positive Histologic Margins and Risk of Future Melanoma Development
Watching, not removing, skin growths with moderate atypia and positive edges is okay; patients may get melanoma elsewhere, especially if they've had it before.
research Dual Aspects of B Cells in Tumor Immunity: Positive and Negative Regulation Against B16 Melanoma
B cells can both help and hinder the body's defense against melanoma.
research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
research Stimulation of Melanogenesis by Carthamus Tinctorius Floret Extract in B16F10 Murine Melanoma Cells
Safflower extract increases melanin production in certain skin cells without harming them.
research Molecular Mapping of Lymph Node Metastases by Real-Time Reverse Transcription Polymerase Chain Reaction in Two Melanoma Patients
The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
research Alopecia Neoplastica Caused by Desmoplastic Melanoma
A rare skin cancer caused hair loss and spread, needing multiple treatments.
research Choroidal Melanoma and Lid Fibrofolliculomas in Birt-Hogg-Dubé Syndrome
A patient with Birt-Hogg-Dubé Syndrome also had choroidal melanoma, suggesting the need for careful eyelid exams in such patients.
research Characteristics of Non-Melanoma Skin Cancers of the Cutaneous Perioral and Vermilion Lip Treated by Mohs Micrographic Surgery
Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.
research Hair Shaft miRNA-221 Levels as a New Tumor Marker of Malignant Melanoma
Hair shaft miR-221 levels can help detect malignant melanoma.
research Excessive Hair Growth Around Local Beta-Interferon Injection Sites for Malignant Melanoma
β-interferon injections for melanoma can cause excessive hair growth at the injection sites.
research Malignant Melanoma
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research Non-Melanoma Skin Cancer in Skin of Color: Cases of Mistaken Identity
Non-melanoma skin cancer in darker-skinned people can be misdiagnosed, so doctors need to be more aware to diagnose it correctly and early.
research Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma
People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.