December 2004 in “Medicine” A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.
February 1990 in “Journal of The American Academy of Dermatology” New skin treatments in 1987-1988 showed effectiveness for various conditions, but some had side effects or risks.
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October 2021 in “Nepal journal of dermatology, venereology & leprology” Melatonin is good for skin health and may help treat skin conditions.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
4 citations,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
February 2016 in “Aktuelle Dermatologie” Be enthusiastic, curious, and engage in research.
106 citations,
January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
82 citations,
March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
16 citations,
October 2004 in “Journal of Investigative Dermatology” Normal human melanocytes can avoid cell death through multiple pathways.
3 citations,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
1 citations,
November 2022 in “Animals” The research found specific genes and pathways that control fur development and color in young American minks.
January 2024 in “Biomedicines” The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.
September 2013 in “International journal of radiation oncology, biology, physics” High dose rate electronic brachytherapy is an effective and safe non-surgical treatment for nonmelanoma skin cancer with good cosmetic results after three years.
76 citations,
March 2005 in “Cancer Research” Doxorubicin can block blood vessels from hair follicles, reducing skin tumor growth.
2 citations,
December 2019 in “Cureus” A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.
April 2016 in “Journal of Investigative Dermatology” MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The study identified key genes and pathways linked to hair disorders, aiding precision medicine.
[object Object] 127 citations,
August 2016 in “The oncologist” Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.
May 2023 in “Australasian Journal of Dermatology” Various substances, including cosmetic sponges, vein glue, chai tea, skincare products, and medicaments, can cause allergic contact dermatitis, and healthcare workers often react to N95 masks.
7 citations,
January 2012 in “International Journal of Trichology” Sudden, unusual hair loss may indicate serious underlying health issues.
3 citations,
March 2019 in “Case Reports” A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.
86 citations,
November 2020 in “Annals of Oncology” Early intervention and tailored management can reduce skin side effects from cancer treatments.
7 citations,
April 2022 in “Cutis” Direct-to-consumer teledermatology is growing fast but raises concerns about quality of care and doctor-patient relationships.
Some blood thinners and blood pressure medicines can cause hair loss, which usually starts 1 to 6 months after beginning the medication.
Some medications, including retinoids, antifungals, and psychotropic drugs, can cause reversible hair loss if stopped or doses are reduced.
The ketogenic diet might improve certain skin conditions, but more research is needed to confirm its effectiveness.
33 citations,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
12 citations,
August 2013 in “Journal of Dermatological Science” The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.