research Cutaneous Adverse Effects of BRAF Inhibitors in Metastatic Malignant Melanoma: A Prospective Study in 20 Patients
BRAF inhibitors for melanoma often cause skin side effects, but they can be managed with proper care.
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research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Targeted Therapy in Melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus
The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
research The Potential Impact of Melanosomal pH and Metabolism on Melanoma
Melanin may help melanoma cells grow by aiding their metabolism.
research Association of Melanoma and Nonmelanoma Skin Cancer with Antihypertensive Drugs: A Report from the Research on Adverse Drug Events and Reports Project
Blood pressure medications may increase the risk of skin cancer.
research NLRP1 Promotes Tumor Growth by Enhancing Inflammasome Activation and Suppressing Caspase-3 Activity in Human Melanoma
NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.
research Association of Melanoma Mortality Rates and Geographic Density of Dermatology and Hematology-Oncology Specialists
More dermatologists in an area are linked to better survival rates for melanoma.
research Bioabsorbable Nano-Micelle Hybridized Hydrogel Scaffold Prevents Postoperative Melanoma Recurrence
A special gel with medicine helps prevent melanoma from coming back after surgery.
research Resolution of Paraneoplastic Alopecia Areata Following Nivolumab in a Patient With Metastatic Melanoma
Nivolumab treatment led to hair regrowth in a man with metastatic melanoma and alopecia areata.
research The Challenging Consultation: Management of Melanoma
The conclusion is that managing hair loss conditions like FFA and melanoma requires individualized approaches, considering new findings and balancing treatment benefits with potential risks.
research Cell of Origin Contributes to Melanoma Diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research Prognostic Significance of a Positive Nonsentinel Lymph Node in Cutaneous Melanoma
Finding a positive nonsentinel lymph node in melanoma patients indicates a worse prognosis.
research Finasteride And Dutasteride May Reduce Melanoma Risk
Finasteride and dutasteride might lower melanoma risk.
research A Prospective Study of Cutaneous Adverse Events Induced by Low-Dose Alpha-Interferon Treatment for Malignant Melanoma
Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.
research Impact of the French COVID-19 Pandemic Lockdown on Newly Diagnosed Melanoma Delay and Severity
The French COVID-19 lockdown caused delays in diagnosing new melanoma cases, making them more severe.
research Blood MUC-18/MCAM Expression in Patients with Melanoma: A Suitable Marker of Poor Outcome
High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
research Clinical Case Notes: Malignant Melanoma in Eviscerated Eyeball
Finasteride, often used for hair loss, can potentially cause cataracts.
research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma
Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
research Anticancer Potential of Musa × Paradisiaca as Cervical Carcinoma and Malignant Melanoma
Banana (Musa × paradisiaca) may help fight cervical cancer and skin cancer.
research Cutaneous Manifestations of Dabrafenib: A Selective Inhibitor of Mutant BRAF in Patients with Metastatic Melanoma
Dabrafenib can cause skin growths and sometimes low-grade skin cancer.
research Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma
Targeted therapies for advanced skin cancer often cause hair and nail problems, which need managing to avoid changing the treatment dose.
research B-RAF, Nevi and Melanoma: A Complex Relationship
Male hair loss is mainly due to thinner hair, not less hair.
research Morphologic Comparison of Cultured Human Epidermis Melanocytes, Amelanotic Melanocytes from Hair Follicles, and Mouse Melanoma Cells Observed by Atomic Force Microscope
Melanin granules can be expelled by exocytosis.
research Multicentric Parallel Phase II Trial of the Polo-Like Kinase 1 Inhibitor BI 2536 in Patients With Advanced Head and Neck Cancer, Breast Cancer, Ovarian Cancer, Soft Tissue Sarcoma, and Melanoma. The First Protocol of the European Organization for Research and Treatment of Cancer Network of Core Institutes
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research In-Vitro Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth
Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.
research Fibroblast Heterogeneity and Functions: Insights from Single-Cell Sequencing in Wound Healing, Breast Cancer, Ovarian Cancer, and Melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research The Dermatological Consequences of Obesity
Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.