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NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.

The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.

Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Cannabinoids might help treat skin problems but more research is needed to be sure.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

Gray hair can potentially be reversed, leading to new treatments.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Finasteride, often used for hair loss, can potentially cause cataracts.