19 citations
,
July 2009 in “Clinical and Experimental Dermatology” This article discusses how the balding scalp's exposure to UV and near-infrared light may accelerate aging, with changes detectable under ultraviolet light; it presents no new clinical findings.
1 citations
,
September 2024 in “Journal of Oncology Pharmacy Practice” In this report, a 77-year-old woman treated for essential thrombocytosis with low-dose hydroxyurea experienced an unexpected change in hair color from gray to dark brown after 20 weeks, highlighting a potential aesthetic side effect of the drug, in addition to therapeutic effects.
January 2011 in “Revista Portuguesa de Endocrinologia Diabetes e Metabolismo” This article presents a case of congenital adrenal hyperplasia and myelolipoma in a 56-year-old woman, describing her symptoms and characteristics without offering new clinical results.
10 citations
,
April 2009 in “Oncology Reports” This study found distinct skin surface changes, including faint mosaic melanoderma and atypical scaliness, on long-standing sun-exposed balding scalps that may be associated with actinic field carcinogenesis.
7 citations
,
November 2011 in “Skin Research and Technology” The authors observed that the patterned melanoderma on the hairless scalp of fair-skinned Caucasian men with androgenic alopecia resembled similar patterns seen on facial skin.
10 citations
,
September 1994 in “International Journal of Dermatology” This case report describes three Iranian men with gradual reddish-brown pigmentation on their cheeks and preauricular areas since childhood, unresponsive to sunblocks and topical steroids.
4 citations
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July 2019 in “Clinics in Dermatology” This article reviews various "white diseases" characterized by hypopigmentation or depigmentation and emphasizes the role of melanosomes in skin and eye color, but it does not present new clinical results.
56 citations
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December 1978 in “The Journal of Dermatologic Surgery and Oncology” This study reported successful and cosmetically acceptable repigmentation of leukoderma in three patients using minigrafts of normally pigmented, autologous skin.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that CCCA in women of African descent is associated with molecular changes, including dysregulation of fatty acid metabolism and fibrosis pathways, suggesting potential targets for new treatments.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that keloids significantly impair quality of life, with pain and itch being major contributors to this impact, comparable to other chronic dermatologic conditions.
1 citations
,
January 2014 in “Elsevier eBooks” This review discusses melanocytes' role in pigmentation, their clinical significance in conditions like vitiligo and hair graying, and highlights current research on hair follicle regeneration without reporting new clinical results.
35 citations
,
July 2007 in “Dermatologic clinics” This review discusses the causes and diagnostic process for facial hypermelanosis, emphasizing the need to rule out systemic disorders like Addison's disease; it reports no new clinical findings.
144 citations
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December 2017 in “Pigment cell & melanoma research” This review suggests that melasma may be a photoaging skin disorder affecting genetically predisposed individuals, which could significantly influence its treatment and prevention strategies.
9 citations
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June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This study examined skin biopsies from a woman with Addison disease and found melanocytic hyperpigmentation in the epidermis, with a notable melanocyte/keratinocyte ratio indicating increased melanocyte presence in the arm compared to the thigh.
November 2021 in “CRC Press eBooks” This review discusses the genetic and metabolic factors influencing hair pigmentation, as well as conditions leading to hypo- or depigmented hair, and reports no new experimental findings.
This article discusses localized repigmentation of hair, suggesting it may be an indicator of underlying melanoma, and emphasizes the need for careful diagnostic evaluation.
This article reviews the variations and risks associated with skin conditions in melanin-rich individuals, including assessment challenges and complications from common skin treatments, but presents no new research findings.
93 citations
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October 2006 in “The International Journal of Biochemistry & Cell Biology” This review discusses melanocyte biology and its genetic and molecular basis, highlighting its relevance in understanding diseases like vitiligo and albinism, and reports no new findings.
164 citations
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February 2010 in “Journal of Cell Science” This study demonstrates that stem cells from human foreskins, which lack hair follicles, can differentiate into melanocytes and migrate to the epidermis, potentially altering our understanding of pigmentation disorders.
8 citations
,
August 2015 in “Journal of dermatological science” This study observed that the topical skin-whitening agent rhododendrol induced skin depigmentation in approximately 16,000 consumers, linked to melanocyte cytotoxicity and immune reactions.
This study reported the case of a 30-year-old man with a bluish-grey scalp nodule that developed over a previously stable hairless plaque, revealing histopathological features consistent with epithelioid cell nests and spindle-shaped dermal melanocytes embedded in collagen.
2 citations
,
January 2002 in “Clinics in Dermatology” This review details the characteristics, associations, and differential diagnoses of vitiligo and reports no new clinical findings.
This study describes vitiligo as a chronic disorder where genetic, environmental, and immune factors contribute to skin depigmentation, with associations to other autoimmune diseases and potential links to oxidative stress.
3 citations
,
December 1967 in “Australasian Journal of Dermatology” This review discusses Becker's Melanosis and Hypertrichosis in young males, summarizing cases observed in Melbourne with clinical and histological analyses, but reports no new clinical findings.
January 2016 in “UNESP Institutional Repository (São Paulo State University)” This study suggests that the phenotype of melasma in women is influenced by structural and cellular changes across the epidermal-melanin unit, not just melanocyte hypertrophy, highlighting potential roles for dermal damage repair and fibroblast senescence.
9 citations
,
July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores the multifaceted roles of melanocytes in skin biology, emphasizing their potential impact on future research to prevent and treat skin diseases, but reports no new experimental results.
June 2023 in “JAAD Case Reports” This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
303 citations
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August 1971 in “The American Journal of Medicine” This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.