research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
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research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research Scarless Wound Healing: Finding the Right Cells and Signals
The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Action Mechanism of Chamaecyparis Obtusa Oil on Hair Growth
Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
research Novel Potential Therapeutic Targets of Alopecia Areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research Immune Niches for Hair Follicle Development and Homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Ultraviolet Radiation in Wound Care: Sterilization and Stimulation
UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
research Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Modeling of Solar UV-Induced Photodamage on the Hair Follicles in Human Skin Organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Skin Biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Hair Removal Using an Nd:YAG Laser System
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Androgenic Alopecia and Stress-Induced Premature Senescence by Cumulative Ultraviolet Light Exposure
Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.
research Differential Expression and Functionality of ATP-Binding Cassette Transporters in the Human Hair Follicle
Certain transporters are found in human hair follicles and may affect hair growth and loss.
research Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Management of Alopecia Due to Cancer Therapies
The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
research Biomaterials for Dermal Substitutes
The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
research A Preliminary Study of Melanogenic Markers in the Differentiation of the Human Hair Follicle Melanin Unit
The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
research Immune Cells May Have a Role in Hair Loss Process Caused by TRPV3 Gain-of-Function Mutation
Immune cells might contribute to hair loss caused by a specific mutation.
research Proceedings From the Third Intercontinental Meeting of Hair Research Societies
The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
research Telocytes in Human Skin – Are They Involved in Skin Regeneration?
Telocytes might help with skin repair and regeneration.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Exosomes as a Novel Pathway for Regulating Development and Diseases of the Skin
Exosomes are important for skin health and could help diagnose and treat skin diseases.