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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
118 citations,
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115 citations,
August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
98 citations,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
98 citations,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
85 citations,
May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
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March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
72 citations,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
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February 2020 in “Journal of Ginseng Research” Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
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July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
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January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
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June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
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March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
59 citations,
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August 2007 in “Dermatologic surgery” New treatments for acne scars are safer and more effective because we understand the causes better.
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July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
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