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Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Hair shedding is an active process that could be targeted to treat hair loss.

Muscles and nerves that cause goosebumps also help control hair growth.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Advanced human skin models improve drug development and could replace animal testing.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.