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Stress-related substance P may lead to hair loss and negatively affect hair growth.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Mutant mice help researchers understand hair growth and related genetic factors.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Hair follicle regeneration needs special conditions and young cells.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Plant-based ingredients are effective and safe for modern skincare products.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.