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30-60 / 1000+ resultsresearch Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles
Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.
research Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
![Hardwiring Stem Cell Communication through Tissue Structure](/images/research/af9bcd06-7fc3-4def-8f06-bda2f0a747d8/small/19621.jpg)
research Hardwiring Stem Cell Communication through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
![MicroRNA/mRNA regulatory networks in the control of skin development and regeneration](/images/research/4e3f01c8-564a-410e-bf6a-3ae6198039fd/small/19847.jpg)
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
![Keratinocytes regulate the function of melanocytes](/images/research/3acb07ba-13aa-4481-b97e-6d1b21581000/small/36001.jpg)
research Keratinocytes regulate the function of melanocytes
Keratinocytes control how melanocytes work.
![Building and Maintaining the Skin](/images/research/b77c9bac-7242-4879-972c-5cf457cfc16b/small/19223.jpg)
research Building and Maintaining the Skin
Three types of stem cells help maintain and repair skin, responding to health and environmental changes.
research 448 Physiological function of krox20 (Egr2) in epithelial stem cells
Krox20 is important for maintaining stem cells in the skin and affects hair growth and color.
![Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments](/images/research/948d24ee-e51a-44a2-84e0-62aac289bcbd/small/18455.jpg)
research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
![Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling](/images/research/c2af2390-b135-47a4-9924-e45cb5ca3a31/small/19842.jpg)
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
![Stem Cells in the Skin](/images/research/14fee45f-7d2c-4af6-aeeb-bcaf12af2105/small/19587.jpg)
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
![Heterogeneity of neural crest-derived melanocytes](/images/research/f4627a63-6cc9-4d59-b4a2-aa40616586a1/small/19782.jpg)
research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
![085 Autoantigen screening in C3H/HeJ mouse model of alopecia areata revealed high antigenicity of melanocyte-associated antigen epitopes](/images/research/9b102364-6b74-4efa-a188-705b1131bbf3/small/35793.jpg)
research 085 Autoantigen screening in C3H/HeJ mouse model of alopecia areata revealed high antigenicity of melanocyte-associated antigen epitopes
Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
![EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling](/images/research/4a84969a-10f2-4f00-a91d-a8f63c55e9cd/small/19618.jpg)
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
![Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro](/images/research/f0a6dc58-7c7d-4306-9a62-6d5a050aef7e/small/19483.jpg)
research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
![Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer](/images/research/60413399-b02d-45fb-83df-da64533a29f7/small/19473.jpg)
research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
![Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying](/images/research/6e413eeb-01ac-4f75-a92a-d8732dfa0162/small/19760.jpg)
research Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying
Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
![Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations](/images/research/ae516e9c-25fb-48ca-86fc-236c7f212f89/small/27880.jpg)
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
![Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential](/images/research/73c6b9a5-a166-40ee-a881-403306d87161/small/35189.jpg)
research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
![Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration](/images/research/3566eb24-d6a1-49dc-b377-22367846c97e/small/19867.jpg)
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
![Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin](/images/research/fd26fa1d-678d-403f-abf3-e6b848b4278b/small/28177.jpg)
research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
![Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia](/images/research/576f7a23-c29b-42f1-b7d5-5d0a714a76ca/small/19841.jpg)
research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
![Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo](/images/research/c899f42e-2014-4262-b4bc-001f173b6d4b/small/19610.jpg)
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
![Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage](/images/research/28e28c1b-7b35-441d-a878-bdb88c59b555/small/36940.jpg)
research Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage
Activating β-catenin increases melanocytes and decreases Schwann cells.
![Hair, Cutaneous Homeostasis and Stem Cell Functions](/images/research/f2a7fe1a-209f-45d5-b9f9-9da0da7ecfe5/small/12835.jpg)
research Hair, Cutaneous Homeostasis and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
![A family business: stem cell progeny join the niche to regulate homeostasis](/images/research/a31e9e48-d1a1-4606-8b9c-3b33e87b570c/small/19845.jpg)
research A family business: stem cell progeny join the niche to regulate homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
![The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis](/images/research/507008ab-9a3f-40a0-aabe-a00697f832c1/small/35061.jpg)
research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
![The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling](/images/research/6f8f9ea0-54fb-4829-8537-c8fb79035379/small/29601.jpg)
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
![Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair](/images/research/889290ad-e210-4d35-8cac-12085c433667/small/19617.jpg)
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.