15 citations
,
January 2013 in “Dermatologic Surgery” This study observed that white hair follicles in vitiligo patients may repigment following epithelial grafting and phototherapy, suggesting potential cosmetic improvements in vitiligo treatment.
41 citations
,
January 2006 in “Dermatology” This study found that noncultured epidermal cell transplantation is promising for treating stable vitiligo, achieving significant repigmentation and patient satisfaction based on objective and subjective evaluations.
8 citations
,
July 2001 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This review summarizes the historical and evolving treatments for vitiligo, highlighting that combining medical and surgical approaches may enhance repigmentation outcomes, though more research and new protocols are needed.
78 citations
,
August 2014 in “Anais Brasileiros de Dermatologia” This article discusses a new global consensus on the classification of vitiligo, describing histopathological findings and outlining treatment strategies, but reports no new clinical results.
60 citations
,
April 2006 in “International Journal of Dermatology” This review discusses various surgical techniques for vitiligo repigmentation, noting that suction blister and split-thickness skin grafting have the highest success rates according to previous analysis, but reports no new results.
48 citations
,
March 1997 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the clinical characteristics, causative factors, and treatment options for vitiligo and reports no new research findings.
37 citations
,
October 2017 in “Advanced drug delivery reviews” This review explores the mechanisms of skin repigmentation and therapeutic strategies for pigmentation disorders following burn injuries, but it presents no new clinical results.
18 citations
,
October 2022 in “Biomedicines” This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.
6 citations
,
October 2006 Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.
2 citations
,
January 2019 in “Springer eBooks” This review discusses segmental vitiligo as part of the vitiligo clinical spectrum and highlights its role as a model for studying repigmentation, but reports no new clinical results.
This chapter reviews surgical management techniques for leukotrichia in vitiligo and presents no new clinical findings; it highlights various grafting and epilation methods.
December 2024 in “Journal of Clinical Medicine of Kazakhstan” This review highlights the potential of combining immune regulation, phototherapy, and dietary strategies for effective vitiligo treatment, but emphasizes that more research is needed.
March 2018 in “John Wiley & Sons, Ltd eBooks” This chapter reviews classification and techniques of surgical therapies for treating stable, recalcitrant vitiligo, highlighting their role alongside non-surgical methods for small, specific cases.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
This article discusses various surgical options for treating leukotrichia in vitiligo patients and reports that hair transplantation shows more promising results, particularly for eyebrows and eyelashes, compared to previous methods.
1 citations
,
February 2025 in “Indian Dermatology Online Journal” This systematic review identified that surgical treatments show a positive response for eyebrow and eyelash leukotrichia, while topical tofacitinib appears promising but requires further research to confirm its efficacy.
7 citations
,
July 2016 in “Journal of Biomedical Materials Research Part A” This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.
1 citations
,
August 2015 in “Experimental Dermatology” This review discusses the roles of KIT and mast cells in skin physiology and pathology using different genetic models and reports no new clinical results; the authors suggest further exploration of KIT deficiency.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study by Refat et al. found that the level of CD8+ T cell infiltrates in vitiligo lesions before surgical treatment can predict the likelihood of successful repigmentation, suggesting a potential new method for identifying patients who may benefit the most from surgical interventions.
June 2005 in “British Journal of Oral & Maxillofacial Surgery” This study found that two years after treatment, the continuous-wave Sharplan 40C SilkTouch laser system led to better collagen organization compared to the pulsed Coherent 5000C UltraPulse system in patients who underwent skin resurfacing.
June 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers detailed various surgical techniques for treating vitiligo, including tissue grafting and cell transplantation. They highlighted recent advancements and emphasized the need for future studies to explore therapeutic mechanisms and identify biomarkers to enhance surgical efficacy.
30 citations
,
December 2001 in “Experimental dermatology” This study found that gonadal steroid hormones influence alopecia areata in C3H/HeJ mice, with estradiol promoting progression and dihydrotestosterone conferring resistance to disease onset.
This study discusses the safety, complications, and limitations of melanocyte transplantation for treating vitiligo, noting that these techniques are generally safe and often combined with medical treatments for repigmenting stable vitiligo macules.
84 citations
,
January 1990 in “Journal of The American Academy of Dermatology” This study reported successful repigmentation without scarring in patients with localized and segmental vitiligo after epidermal grafting, but the Koebner phenomenon hindered similar results in some with generalized vitiligo.
5 citations
,
January 2012 in “Journal of Tissue Science & Engineering” In this study, collagen I decellularized scaffolds enhanced the growth and melanotic properties of hair follicle melanocytes, suggesting their potential as effective carriers for transplantation in vitiligo treatment.
67 citations
,
November 2019 in “Nature Communications” This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” This review discusses melanocyte development, emphasizing the plasticity of melanoblasts and the role of both intrinsic and extracellular signals in their differentiation and migration, with no new clinical results reported.
66 citations
,
December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” This study found that ionizing radiation primarily affects keratinocyte stem cells in the hair follicle, suggesting they play a central role in radiation-induced hair graying, rather than melanocyte stem cells.
26 citations
,
February 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Technique effectively treats deformities, achieves re-pigmentation, and releases scar contractures.