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      Severe Cutaneous Adverse Reactions to Drugs

      research Severe cutaneous adverse reactions to drugs

      273 citations , May 2017 in “The Lancet”
      This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
      Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

      research Transforming growth factor-β in stem cells and tissue homeostasis

      245 citations , January 2018 in “Bone Research”
      This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
      Tracing the Cellular Origin of Cancer

      research Tracing the cellular origin of cancer

      232 citations , January 2013 in “Nature Cell Biology”
      Understanding where cancer cells come from helps create better prevention and treatment methods.
      Signaling Involved in Hair Follicle Morphogenesis and Development

      research Signaling Involved in Hair Follicle Morphogenesis and Development

      223 citations , January 2014 in “International Journal of Molecular Sciences”
      This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
      Cutaneous Adverse Effects of Targeted Therapies

      research Cutaneous adverse effects of targeted therapies

      192 citations , January 2015 in “Journal of the American Academy of Dermatology”
      This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.
      The PDGF/PDGFR Pathway as a Drug Target

      research The PDGF/PDGFR pathway as a drug target

      182 citations , November 2017 in “Molecular Aspects of Medicine”
      This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      Vitamin D and the Skin: Physiology and Pathophysiology

      research Vitamin D and the skin: Physiology and pathophysiology

      158 citations , August 2011 in “Reviews in endocrine and metabolic disorders”
      This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.
      The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
      Obesity and the Skin

      research Obesity and the skin

      128 citations , September 2011 in “British Journal of Dermatology”
      Obesity is linked to various skin problems and may increase the risk of skin cancer.
      From Causes of Aging to Death from COVID-19

      research From causes of aging to death from COVID-19

      122 citations , June 2020 in “Aging”
      This review discusses the hyperfunction theory of aging as a key factor in COVID-19 vulnerability, highlighting the potential of anti-aging interventions like rapamycin to reduce this risk.
      Smoking and the Skin: Effects and Therapeutic Potential

      research Smoking and the skin

      114 citations , February 2012 in “International Journal of Dermatology”
      This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.
      Drug-Induced Skin, Nail, and Hair Disorders

      research Drug-Induced Skin, Nail and Hair Disorders

      114 citations , January 2007 in “Drug Safety”
      This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.
      S1 Guideline Long/Post-COVID

      research S1-Leitlinie Long-/Post-COVID

      96 citations , December 2022 in “Pneumologie”
      This guideline review discusses current symptoms, diagnostic approaches, and treatments for Long- and Post-COVID, based on today's knowledge, and emphasizes its practical application with ongoing updates as new insights emerge.
      Elemental Hair Analysis: A Review of Procedures and Applications

      research Elemental hair analysis: A review of procedures and applications

      96 citations , September 2017 in “Analytica Chimica Acta”
      This review discusses the growing use of scalp hair for elemental analysis in various fields and highlights advancements in analysis techniques, including the future potential of laser ablation ICP-MS, but reports no new clinical results.
      Turing Patterns in Development: What About the Horse Part?

      research Turing patterns in development: what about the horse part?

      92 citations , December 2012 in “Current opinion in genetics & development”
      This review covers the recent advances in understanding how Turing models may explain various morphogenetic processes, but it reports no new experimental findings.