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Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Type B Insulin Resistance Syndrome is rare, linked to lupus, and hard to treat due to severe insulin resistance.

Classical PCOS types A and B are most common and linked to higher health risks.

Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.

Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

New therapies are being developed that target integrin pathways to treat various diseases.

THSG from a Chinese plant helps with aging and related diseases.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Testosterone's effects on COVID-19 are unclear and need more research.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

Coffee berry extract may help slow skin aging and prevent hair loss.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.