![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
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research 4-(Alkylthio)- and 4-(Arylthio)-Benzonitrile Derivatives as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
research Preparation of 4-Aryl-2-Trifluoromethylbenzonitrile Derivatives as Androgen Receptor Antagonists for Topical Suppression of Sebum Production
Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
![Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety](/images/research/2ecf4eed-7dbe-4f1a-83db-739625546cdd/small/31808.jpg)
research Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety
Analog 23 is a promising compound for prostate cancer treatment.
research Diphenyl Ethers as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement
Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
research Morinda Pubescens J.E. Smith (Morinda Tinctoria Roxb.) Fruit Extract Accelerates Wound Healing in Rats
Morinda pubescens fruit extract helps wounds heal faster in rats.
research Novel Lead Generation Through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase
Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Chapter 20: Advances in Dermatological Treatments
New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research Evaluation of the Permeability of Hair Growing Ingredient Encapsulated PLGA Nanospheres to Hair Follicles and Their Hair Growing Effects
PLGA nanospheres improve hair growth by effectively delivering ingredients to hair follicles.
research The Preclinical and Clinical Effects of Herbal Product Containing Rosa Multiflora Roots Extracts on Hair Growth Promotion
Rosa multiflora root extract promotes hair growth and prevents hair loss.
research Aesthetic Rehabilitation Medicine: Enhancing Wellbeing Beyond Functional Recovery
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
research Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
The study suggests that analyzing DNA can help treat hair loss, but more research is needed.
research Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators
Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
research Repurposing of Various Current Medicines as Radioprotective Agents
Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.
research Characteristics And Alopecia Activity Of Pakis Gajah (Angiopteris Evecta) Growing In Galunggung Mountainside, West Java
Pakis Gajah (Angiopteris evecta) water extract may promote hair growth in rabbits, but more research is needed for human use.
research Saw Palmetto (Serenoa Repens) in Androgenic Alopecia: An Effective Phytotherapy
Saw palmetto is an effective natural treatment for hair loss with minimal side effects.
research Human Hair: An Important Biological Matrix of Interest
Human hair is a significant sample for various tests in clinical, nutritional, archaeological, and forensic studies.
research Use of Phytotherapeutics, Low Power Laser, and Ozone for Biting Wound in Dog
A dog's chronic bite wound healed successfully using a mix of herbal gel, low power laser, and ozone therapy.
research Investigating the Effects of Hydro-Alcoholic Extract of Pimpinella Anisum L. on Hair Growth
Pimpinella anisum L. extract significantly boosts hair growth in mice.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Review of Pharmacological Effects of Myrtus Communis L. and Its Active Constituents
Myrtle has various health benefits and potential for medicine development.
research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Hair Growth Promoting Activity of Eclipta Alba in Male Albino Rats
Eclipta alba extract helps hair grow faster and more effectively than minoxidil in rats.
research Anticandidal Activity of Santolina Chamaecyparissus Volatile Oil
Santolina chamaecyparissus oil effectively fights fungal infections.
research Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment
Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.