Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.

In this study, Artemisia sieversiana extract was found to safely promote hair follicle dermal papilla cell growth and inhibit hair loss through anti-androgen, anti-inflammatory, and antioxidant effects at a cellular level.

D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.

In a testosterone-induced mouse model of androgenetic alopecia, this study found that oral and topical administration of Connarus semidecandrus Jack ethanol extract promoted hair regrowth and improved hair health markers similar to finasteride, without detectable liver or kidney toxicity.

This systematic review found that interventions targeting neuropeptides and neurotransmitters, particularly melatonin, substance P, and oxytocin, show consistent evidence for anti-inflammatory, reparative, and psychodermatologic benefits, highlighting the potential of neurohormonal signaling as a therapeutic target in dermatology.

This study suggests that extracellular vesicles derived from Saccharomyces cerevisiae may enhance hair follicle-related cellular processes, highlighting their potential for biomedical and cosmetic applications.

This review discusses the use of platelet-rich plasma in regenerative dentistry, highlighting its biological principles, clinical applications, and the challenges encountered in PRP-based strategies for oral tissue engineering, but reports no new results.

This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.

This review discusses the characteristics, complications, and treatment options for hidradenitis suppurativa, a chronic skin disorder with systemic effects, without presenting new clinical findings.

This paper outlines the chronic inflammatory skin disorder hidradenitis suppurativa, emphasizing its symptomatology, associated systemic diseases, known risk factors, and treatment strategies, including medical and surgical interventions depending on disease severity, while highlighting its significant impact on patients' quality of life.

This review discusses the role of vitamin D receptor signaling in hair follicle biology for alopecia treatment and underscores the need for continued research, without presenting new clinical results.

This study offers a new perspective on androgenetic alopecia, suggesting that hair loss at the vertex and frontal scalp results from mechanical and thermodynamic stress, alongside androgen activity, and proposes that reducing mechanical tension and improving local microcirculation could complement traditional treatments.

Light skin shows more inflammation from sun exposure than dark skin.

This study reviewed how neuropeptides and cutaneous innervation play crucial roles in the process of wound healing, suggesting they significantly influence inflammation and tissue repair phases.

This review discusses the role of regulatory T cells, highlighting recent research on how prostanoids may modulate their function, but it reports no new findings.

This study found that transgenic mice overexpressing IKZF1 developed lesions similar to alopecia areata, suggesting that Ikaros may play a role in the disease's pathogenesis. Ikaros expression was also higher in human alopecia areata patients compared to controls.

In this study, Derma Genie™-H001 was shown to reduce inflammation, counteract oxidative and UVB-induced damage, and support hair growth-related gene expression in human dermal papilla cells, suggesting its potential as a functional cosmetic ingredient to alleviate hair loss symptoms.

This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.

In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.

This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.

This study shows that IKZF1 and the protein IKAROS may play a role in the development of alopecia areata, based on findings from both mouse models and human scalp tissues.

This study explores the use of in silico methods to identify potential diagnostic biomarkers for primary cicatricial alopecia, revealing significant interactions among genes and proteins related to disease pathogenesis.

This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.

This mini review discusses cellular plasticity in cutaneous wound healing and reports no clinical results; the authors aim to enhance regenerative medicine by examining underlying mechanisms.

This study found that the RNA helicase DDX6 is essential for maintaining self-renewal in epidermal progenitor cells by promoting the translation of proliferation regulators and degrading differentiation-inducing mRNAs.

This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.

This review discusses various hormonal and neuropeptide influences on hair growth and reports no new clinical results; it highlights complexity and suggests areas for future exploration.

This study suggests that selenium deficiency accelerates aging-related health deterioration in mice with short telomeres, providing a model for exploring selenium’s role in human aging.

This study found that among HIV-infected women, central lipohypertrophy was associated with shorter eyelashes but not changes in scalp hair texture or inflammation.

This study found that SRD5A2 expression is absent in one third of benign adult prostates and is associated with hypermethylation, suggesting potential personalization of treatment for prostatic diseases based on methylation status.